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Odd, eccentric specialist Dr. Karn guides unknowing patients through the reincarnation transition. When Harrison experiences mysterious recurring dreams, he turns to Dr. Karn for help and reveals his encounter with a woman he loved in a previous life. Noticing a glitch in the system, the doctor must fix the issue before permanently derailing his patient's future.
After the tragic overdose of his estranged friend, Will, a recovering addict, returns home, where he is reunited with Claire, his friend's grieving mother, with whom he begins a secret but volatile affair.
When Alita awakens with no memory of who she is in a future world she does not recognize, she is taken in by Ido, a compassionate doctor who realizes that somewhere in this abandoned cyborg shell is the heart and soul of a young woman with an extraordinary past.
After workaholic Kevin has a drunken one night stand with the beautiful train-wreck Madeline, he's horrified to discover that she's actually his boss' jilted ex-mistress. When she takes a bottle of sleeping pills, Kevin is forced to keep her awake... and over the course of the night the two begin to fall for each other.